VIP (Vasoactive Intestinal Peptide) – Research Peptide for Pulmonary, Immune & Neurological Research

Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28-amino-acid neuropeptide extensively studied for its role in cellular communication, inflammatory regulation, vascular function, and neurobiological signaling. VIP is widely distributed throughout the gastrointestinal tract, respiratory system, cardiovascular tissues, pancreas, and central nervous system, making it a valuable compound for multidisciplinary research applications.

In laboratory settings, VIP is recognized for its interaction with VPAC1 and VPAC2 receptors, which are expressed across pulmonary, immune, and neuronal tissues. Activation of these receptors has been associated with cyclic AMP (cAMP) signaling pathways, cytokine regulation, smooth muscle activity, vascular responses, and cellular homeostasis.

Research Overview

VIP has become an important research tool in studies focused on:

• Pulmonary and respiratory system biology
• Immune cell signaling and cytokine regulation
• Gastrointestinal function and mucosal integrity
• Neuroprotection and nervous system homeostasis
• Inflammatory pathway modulation
• Vascular tone and smooth muscle regulation
• Cell-to-cell communication and receptor signaling

Its broad biological activity makes VIP a valuable molecule for investigating interactions between the nervous, immune, and vascular systems.

Potential Research Applications

Researchers commonly investigate VIP in models involving:

Pulmonary Research

• Bronchoconstriction and airway function studies
• Pulmonary inflammation models
• Pulmonary vascular signaling research
• Respiratory immune response investigations

Immune System Research

• Cytokine expression and regulation studies
• Immune cell communication pathways
• Inflammatory response modulation
• Innate and adaptive immune signaling research

Gastrointestinal Research

• Gastrointestinal motility studies
• Mucosal barrier function investigations
• Intestinal immune regulation models
• Epithelial integrity and cellular signaling research

Neurological Research

• Neuroinflammation pathway studies
• Neuroprotective signaling investigations
• Central nervous system homeostasis research
• Neuronal survival and cellular resilience models

Key Features

✔ Naturally occurring 28-amino-acid neuropeptide
✔ Targets VPAC1 and VPAC2 receptor pathways
✔ Widely studied in pulmonary, immune, gastrointestinal, and neurological research
✔ Suitable for advanced cellular signaling and inflammatory pathway investigations
✔ High-purity research-grade material for laboratory applications

Scientific Significance

VIP remains a significant focus in modern peptide research due to its diverse physiological roles and receptor-mediated effects. Its involvement in inflammatory regulation, vascular function, pulmonary signaling, and neurobiological pathways continues to drive interest across academic, biotechnology, and pharmaceutical research environments.

Research Use Disclaimer

For laboratory research use only. Not for human consumption. Not intended for medical, therapeutic, veterinary, or diagnostic applications. This product is supplied exclusively for scientific research and development purposes.